I think the opening scene of Season 6 will make us think that Daniel’s Plan worked and things have changed.
Let’s recap, and please tell me where I've made mistakes.

Season 1 started with Jack’s eye.
Season 1 ended with Locke blowing up the hatch.
Season 2 started with Desmond in the hatch right before and after they blew up the hatch.
Season 2 ended with Jack, Sawyer, Kate, and Hurley being captured by the Others and Desmond blowing up the Swan by turning the failsafe.
Season 3 started with Juliet watching 815 crash.
Season 3 ended with bushy beard Jack and “We have to go baaack!”
Season 4 started with Hurley having a car chase, while Jack watched it on the news.
Season 4 ended with Jack and Ben looking at Locke’s body in the coffin.
Season 5 started with Dr. Chang waking up.
Season 5 ended with Juliet supposedly blowing up the Swan site.
Each season ending is following by a loosely match start of the next season. We always have a twist in the opening scene.
So, I bet we are lead to believe things changed.
I see either the opening scene to be Bernard freaking out and telling Rose he has to go to the bathroom, Jack drinking a cocktail, etc. Then we see Jack’s eye opening up, and as it the camera slowly zooms out, we see Jack isn’t wearing a suit, but the Dharma jumpsuit. They just flashed to 2007, Jack, Kate, Sawyer, Jin, Hurley, Sayid and Miles are at the crater of the Swan which Desmond blew up. They go to the beach, see people paddling out, and James tries to stop them, so Juliet won’t die.
Or
We see Desmond in the Hatch, listening to music, riding the bike, taking a shower, etc. The twist is that he was dreaming about the Swan wakes up and tells Penny they ALL have to go back to the Island. I really feel Desmond has to return to the Island and he won’t unless Penny and Charlie are in danger.